A rapidly progressive, invariably fatal neurological disease that attacks the nerve cells (neurons) responsible for controlling voluntary muscles. The disease belongs to a group of disorders known as motor neuron diseases, which are characterized by the gradual degeneration and death of motor neurons. Mental status of the patient is intact and not affected.
ALS results from degeneration of:
- upper motor neurons in the medulla oblongata
- lower motor neurons in the spinal cord
Muscle atrophy (loss of muscle tone)
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